Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate

The neural tube is composed of a number of neural progenitors and postmitotic neurons distributed in a quantitatively and spatially precise manner. The floor plate, located in the ventral-most region of the neural tube, has a lot of unique characteristics, including a low cell proliferation rate. Th...

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Bibliographic Details
Main Authors: Minori Kadoya, Noriaki Sasai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01022/full