Circ_0000144 acts as a miR-1178-3p decoy to promote cell malignancy and angiogenesis by increasing YWHAH expression in papillary thyroid cancer

Circ_0000144 acts as a miR-1178-3p decoy to promote cell malignancy and angiogenesis by increasing YWHAH expression in papillary thyroid cancer

Highlights 1. Inhibition of circ_0000144 repressed malignant behaviors and angiogenesis of PTC cells in vitro. 2. Knockdown of circ_0000144 constrained PTC cell proliferation in vivo. 3. Circ_0000144 acted as a miR-1178-3p sponge. 4. YWHAH acted as a downstream target for miR-1178-3p.

Bibliographic Details
Main Authors: Yinli Ma, Dan Yang, Pingan Guo
Format: Article
Language:English
Published: SAGE Publishing 2022-07-01
Series:Journal of Otolaryngology - Head and Neck Surgery
Subjects:
PTC
Circ_0,000,144
miR-1178-3p
YWHAH
Angiogenesis
Online Access:https://doi.org/10.1186/s40463-022-00574-w

Internet

https://doi.org/10.1186/s40463-022-00574-w

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