Paternal preconception phthalate exposure alters sperm methylome and embryonic programming

Preconception environmental conditions have been demonstrated to shape sperm epigenetics and subsequently offspring health and development. Our previous findings in humans showed that urinary anti-androgenic phthalate metabolites in males were associated with altered sperm methylation and blastocyst...

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Bibliographic Details
Main Authors: Oladele A. Oluwayiose, Chelsea Marcho, Haotian Wu, Emily Houle, Stephen A. Krawetz, Alexander Suvorov, Jesse Mager, J. Richard Pilsner
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Environment International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412021003184