The protective roles of allicin on type 1 diabetes mellitus through AMPK/mTOR mediated autophagy pathway

The protective roles of allicin on type 1 diabetes mellitus through AMPK/mTOR mediated autophagy pathway

Background: Type 1 diabetes mellitus (T1DM) is one of the most common endocrine and metabolic diseases in children. Pancreatic β cells are thought to be critical cells involved in the progression of T1DM, and their injury would directly lead to impaired insulin secretion.Purpose: To investigate the...

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Bibliographic Details
Main Authors: Rengcheng Qian, Huihui Chen, Hongzhou Lin, Yalan Jiang, Pingping He, Yinjuan Ding, Huilan Wu, Yongmiao Peng, Lingfei Wang, Congde Chen, Dexuan Wang, Weiping Ji, Xiaoling Guo, Xiaoou Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
type 1 diabetes mellitus (T1DM)
allicin
pancreatic β cells
autophagy
AMPK/mTOR pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1108730/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1108730/full

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