Hypothermic machine perfusion alleviates ischemia-reperfusion injury of intestinal transplantation in pigs

Hypothermic machine perfusion alleviates ischemia-reperfusion injury of intestinal transplantation in pigs

BackgroundIntestinal transplantation (IT) has become an important procedure for the treatment of irreversible intestinal failure. However, IT is extremely vulnerable to ischemia–reperfusion injury (IRI). Due to the limitations of static cold storage (SCS), hypothermic machine perfusion (HMP) is rapi...

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Bibliographic Details
Main Authors: Wen Hou, Shuang Yang, Jiansen Lu, Yuan Shi, Jing Chen, Decheng Chen, Fei Wang, Lei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
hypothermic machine perfusion
intestinal transplantation
ischemia reperfusion (I/R) injury
pig
TLR4/NF κB pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1117292/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1117292/full

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