Frequency and geographic distribution of gyrA and gyrB mutations associated with fluoroquinolone resistance in clinical Mycobacterium tuberculosis isolates: a systematic review.

The detection of mutations in the gyrA and gyrB genes in the Mycobacterium tuberculosis genome that have been demonstrated to confer phenotypic resistance to fluoroquinolones is the most promising technology for rapid diagnosis of fluoroquinolone resistance.In order to characterize the diversity and...

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Bibliographic Details
Main Authors: Elisea Avalos, Donald Catanzaro, Antonino Catanzaro, Theodore Ganiats, Stephanie Brodine, John Alcaraz, Timothy Rodwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376704?pdf=render