Cytotoxic Effects of Diclofenac and Ibuprofen Zinc (II)-Nicotinamide Ternary Complexes in Breast Cancer Cell Lines

Cytotoxic Effects of Diclofenac and Ibuprofen Zinc (II)-Nicotinamide Ternary Complexes in Breast Cancer Cell Lines

Abstract Breast cancer is one of the leading types of cancer worldwide, and the search for new treatment options are crucial. Nonsteroidal anti-inflammatory drugs (NSAIDs) -specially ibuprofen and diclofenac-, have shown antitumoral effect against several types of cancer. The synthesis of organometa...

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Bibliographic Details
Main Authors: Emanuelle Fraga da Silva, Paulo Roberto dos Santos, Krist Helen Antunes Fernandes, Deise do Nascimento de Freitas, Rafael Fernandes Zanin, Pablo Machado, Sidnei Moura, Ana Paula Duarte de Souza
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2021-12-01
Series:Brazilian Archives of Biology and Technology
Subjects:
NSAIDs
Zinc complexes
cytotoxicity
coordination compounds
cell viability
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100423&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100423&tlng=en

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