BIOLOGICAL EFFECTS OF TNF-BINDING VARIOLAVIRUS RECOMBINANT PROTEIN

Abstract. This review presents a summary of our data concerning in vivo and in vitro effects of recombinant TNF-binding protein from variola virus (VARVCrmB) upon TNF-induced functional changes of human and murine cells. VARV-CrmB protein blocks TNF-induced production of IL-1β and IL-6 by human mono...

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Main Authors: I. A. Orlovskaya, D. D. Tsyrendorzhiev, L. B. Toporkova, V. V. Kurilin, Y. A. Lopatnikova, E. A. Vyazovaya, I. P. Gileva, S. N. Schelkunov, S. V. Sennikov
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
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Online Access:https://www.mimmun.ru/mimmun/article/view/292