CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer

CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer

Chromodomain-helicase-DNA-binding protein 1 (CHD1) deletion is among the most common mutations in prostate cancer (PCa), but its role remains unclear. In this study, RNA sequencing was conducted in PCa cells after clustered regularly interspaced palindromic repeat (CRISPR)/CRISPR-associated protein...

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Bibliographic Details
Main Authors: Yu-Zhao Wang, Yu-Chen Qian, Wen-Jie Yang, Lei-Hong Ye, Guo-Dong Guo, Wei Lv, Meng-Xi Huan, Xiao-Yu Feng, Ke Wang, Zhao Yang, Yang Gao, Lei Li, Yu-Le Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Asian Journal of Andrology
Subjects:
angiogenesis; chd1; hif1α; metabolism; prostate cancer
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=2;spage=152;epage=157;aulast=Wang

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=2;spage=152;epage=157;aulast=Wang

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