Simultaneous determination of oxysterols, cholesterol and 25-hydroxy-vitamin D3 in human plasma by LC-UV-MS.

Simultaneous determination of oxysterols, cholesterol and 25-hydroxy-vitamin D3 in human plasma by LC-UV-MS.

Oxysterols are promising biomarkers of neurodegenerative diseases that are linked with cholesterol and vitamin D metabolism. There is an unmet need for methods capable of sensitive, and simultaneous quantitation of multiple oxysterols, vitamin D and cholesterol pathway biomarkers.A method for simult...

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Bibliographic Details
Main Authors: Rohini Narayanaswamy, Vignesh Iyer, Prachi Khare, Mary Lou Bodziak, Darlene Badgett, Robert Zivadinov, Bianca Weinstock-Guttman, Todd C Rideout, Murali Ramanathan, Richard W Browne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395275?pdf=render

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http://europepmc.org/articles/PMC4395275?pdf=render

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