Molecular Structure-Based Screening of the Constituents of <i>Calotropis procera</i> Identifies Potential Inhibitors of Diabetes Mellitus Target Alpha Glucosidase

Molecular Structure-Based Screening of the Constituents of <i>Calotropis procera</i> Identifies Potential Inhibitors of Diabetes Mellitus Target Alpha Glucosidase

Diabetes mellitus is a disorder characterized by higher levels of blood glucose due to impaired insulin mechanisms. Alpha glucosidase is a critical drug target implicated in the mechanisms of diabetes mellitus and its inhibition controls hyperglycemia. Since the existing standard synthetic drugs hav...

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Bibliographic Details
Main Authors: Cynthia A. Adinortey, Gabriel B. Kwarko, Russell Koranteng, Daniel Boison, Issaka Obuaba, Michael D. Wilson, Samuel K. Kwofie
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Current Issues in Molecular Biology
Subjects:
diabetes
<i>Calotropis procera</i>
alpha glucosidase
cheminformatics
molecular docking
molecular dynamics simulations
Online Access:https://www.mdpi.com/1467-3045/44/2/64

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https://www.mdpi.com/1467-3045/44/2/64

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