Current Understanding of Hypoxia in Glioblastoma Multiforme and Its Response to Immunotherapy

Hypoxia is a hallmark of glioblastoma multiforme (GBM), the most aggressive cancer of the central nervous system, and is associated with multiple aspects of tumor pathogenesis. For example, hypoxia induces resistance to conventional cancer therapies and inhibits antitumor immune responses. Thus, tar...

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Bibliographic Details
Main Authors: Jang Hyun Park, Heung Kyu Lee
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/5/1176