Danger signals and graft-versus-host disease: Current understanding and future perspectives

Graft-versus-host response after allogeneic hematopoietic stem cell transplantation (allo-HCT) represents one of the most intense inflammatory responses observed in humans. Host conditioning facilitates engraftment of donor cells but the tissue injury causes from it primes the critical first steps i...

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Bibliographic Details
Main Authors: Tomomi Toubai, Nathan Mathewson, John Magenau, Pavan Reddy
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00539/full