Early Endosomes Undergo Calcium‐Triggered Exocytosis and Enable Repair of Diffuse and Focal Plasma Membrane Injury

Early Endosomes Undergo Calcium‐Triggered Exocytosis and Enable Repair of Diffuse and Focal Plasma Membrane Injury

Abstract Cells are routinely exposed to agents that cause plasma membrane (PM) injury. While pore‐forming toxins (PFTs), and chemicals cause nanoscale holes dispersed throughout the PM, mechanical trauma causes focal lesions in the PM. To examine if these distinct injuries share common repair mechan...

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Bibliographic Details
Main Authors: Daniel C. Bittel, Jyoti K. Jaiswal
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Advanced Science
Subjects:
calcium
early endosomes
endocytosis
exocytosis
pore forming toxins
wounds
Online Access:https://doi.org/10.1002/advs.202300245

Internet

https://doi.org/10.1002/advs.202300245

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