Short-course, high-dose primaquine regimens for the treatment of liver-stage vivax malaria in children

Short-course, high-dose primaquine regimens for the treatment of liver-stage vivax malaria in children

Objectives: To assess the pharmacokinetics, safety, and tolerability of two high-dose, short-course primaquine (PQ) regimens compared with standard care in children with Plasmodium vivax infections. Methods: We performed an open-label pediatric dose-escalation study in Madang, Papua New Guinea (Clin...

Full description

Bibliographic Details
Main Authors: Brioni R. Moore, Sam Salman, Roselyn Tobe, John Benjamin, Gumul Yadi, Bernadine Kasian, Moses Laman, Leanne J. Robinson, Madhu Page-Sharp, Inoni Betuela, Kevin T. Batty, Laurens Manning, Ivo Mueller, Timothy M.E. Davis
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:International Journal of Infectious Diseases
Subjects:
Primaquine
Vivax malaria
Children
Pharmacokinetics
Safety
Short-course regimen
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223005714

Internet

http://www.sciencedirect.com/science/article/pii/S1201971223005714

Similar Items