LGR5 expression and clinicopathological features of the invasive front in the fat infiltration area of pancreatic cancer

LGR5 expression and clinicopathological features of the invasive front in the fat infiltration area of pancreatic cancer

Abstract Background Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a strong cancer stem cell marker in colorectal cancer; however, there are many unclear aspects of LGR5 expression in pancreatic cancer. It has been reported that the interaction between tumor cells and stroma a...

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Bibliographic Details
Main Authors: Masato Kamakura, Takeshi Uehara, Mai Iwaya, Shiho Asaka, Shota Kobayashi, Tomoyuki Nakajima, Yasuhiro Kinugawa, Tadanobu Nagaya, Takahiro Yoshizawa, Akira Shimizu, Hiroyoshi Ota, Takeji Umemura
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Diagnostic Pathology
Subjects:
Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5)
RNA in situ hybridization
Pancreatic ductal adenocarcinoma
cancer stem cell
Fat invasion
Online Access:https://doi.org/10.1186/s13000-022-01203-w

Internet

https://doi.org/10.1186/s13000-022-01203-w

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