Gallic Acid Alleviates Visceral Pain and Depression via Inhibition of P2X7 Receptor

Gallic Acid Alleviates Visceral Pain and Depression via Inhibition of P2X7 Receptor

Chronic visceral pain can occur in many disorders, the most common of which is irritable bowel syndrome (IBS). Moreover, depression is a frequent comorbidity of chronic visceral pain. The P2X7 receptor is crucial in inflammatory processes and is closely connected to developing pain and depression. G...

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Bibliographic Details
Main Authors: Lequan Wen, Lirui Tang, Mingming Zhang, Congrui Wang, Shujuan Li, Yuqing Wen, Hongcheng Tu, Haokun Tian, Jingyi Wei, Peiwen Liang, Changsen Yang, Guodong Li, Yun Gao
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
gallic acid
P2X7 receptor
visceral pain
depression
hippocampus
spinal cord
Online Access:https://www.mdpi.com/1422-0067/23/11/6159

Internet

https://www.mdpi.com/1422-0067/23/11/6159

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