Synthesis of novel indole, 1,2,4-triazole derivatives as potential glucosidase inhibitors

Synthesis of novel indole, 1,2,4-triazole derivatives as potential glucosidase inhibitors

Objective: In the present study a series of eleven bis-heterocyclic compounds with indole derivative carrying 1,2,4-triazole moiety were synthesized and assessed for their in vitro α-amylase and α-glucosidase inhibition activity. Method: The synthesized compounds were characterized by using various...

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Bibliographic Details
Main Authors: Ramesh S Gani, Karabasanagouda Timanagouda, S. Madhushree, Shrinivas D Joshi, Murigendra B. Hiremath, Salma Begum Hussain Mujawar, Avinash Kundadka Kudva
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of King Saud University: Science
Subjects:
α-Amylase
α-Glucosidase
Molecular docking
Indole
Triazole
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364720303049

Internet

http://www.sciencedirect.com/science/article/pii/S1018364720303049

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