SCREENING FOR KEY GENES INVOLVED IN PROPOFOL-INDUCED NEUROTOXICITY BASED ON METABOLOMICS AND TRANSCRIPTOMICS

Objective To screen for the key genes involved in propofol-induced neurotoxicity based on metabolomics and transcriptomics. Methods HT22 cells were cultured with propofol at concentrations of 0, 25, 50, 75, and 100 mg/L for 24 h and were established as Ctrl, P25, P50, P75, and P100 groups, respectiv...

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Bibliographic Details
Main Author: LI Shenfeng, ZHUANG Zhao, DIAO Yujing, CAO Hong, WANG Shoushi
Format: Article
Language:zho
Published: Editorial Office of Journal of Precision Medicine 2023-08-01
Series:精准医学杂志
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Online Access:https://jpmed.qdu.edu.cn/fileup/2096-529X/PDF/202304010.pdf