Telomerase-based vaccines: a promising frontier in cancer immunotherapy

Abstract Telomerase, an enzyme crucial for maintaining telomere length, plays a critical role in cellular immortality and is overexpressed in most cancers. This ubiquitous presence makes telomerase, and specifically its catalytic subunit, human telomerase reverse transcriptase (hTERT), an attractive...

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Bibliographic Details
Main Authors: Sogand Vahidi, Arefeh Zabeti Touchaei
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-024-03624-7