Circulating oxylipin and bile acid profiles of dexmedetomidine, propofol, sevoflurane, and S-ketamine: a randomised controlled trial using tandem mass spectrometry

Circulating oxylipin and bile acid profiles of dexmedetomidine, propofol, sevoflurane, and S-ketamine: a randomised controlled trial using tandem mass spectrometry

Background: This exploratory study aimed to investigate whether dexmedetomidine, propofol, sevoflurane, and S-ketamine affect oxylipins and bile acids, which are functionally diverse molecules with possible connections to cellular bioenergetics, immune modulation, and organ protection. Methods: In t...

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Bibliographic Details
Main Authors: Aleksi Nummela, Lauri Laaksonen, Annalotta Scheinin, Kaike Kaisti, Tero Vahlberg, Mikko Neuvonen, Katja Valli, Antti Revonsuo, Markus Perola, Mikko Niemi, Harry Scheinin, Timo Laitio
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:BJA Open
Subjects:
bile acids
dexmedetomidine
lipidomics
oxylipins
propofol
sevoflurane
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609622001137

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http://www.sciencedirect.com/science/article/pii/S2772609622001137

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