Non-targeted effects of photon and particle irradiation and the interaction with the immune system

Ionizing irradiation is an important clinical approach to treat solid tumors. Modern radiation technologies aim to selectively kill tumor cells and protect the surrounding normal tissue. The standard paradigm for radiation effects in cellular systems involves damage of the DNA including DNA double s...

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Bibliographic Details
Main Authors: Thomas Ernst Schmid, Gabriele eMulthoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00080/full