Effects of clozapine-N-oxide and compound 21 on sleep in laboratory mice

Effects of clozapine-N-oxide and compound 21 on sleep in laboratory mice

Designer receptors exclusively activated by designer drugs (DREADDs) are chemogenetic tools for remote control of targeted cell populations using chemical actuators that bind to modified receptors. Despite the popularity of DREADDs in neuroscience and sleep research, potential effects of the DREADD...

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Bibliographic Details
Main Authors: Janine Traut, Jose Prius Mengual, Elise J Meijer, Laura E McKillop, Hannah Alfonsa, Anna Hoerder-Suabedissen, Seo Ho Song, Kristoffer D Fehér, Dieter Riemann, Zoltan Molnar, Colin J Akerman, Vladyslav V Vyazovskiy, Lukas B Krone
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
sleep
chemogenetics
DREADD
clozapine-N-oxide
compound 21
EEG
Online Access:https://elifesciences.org/articles/84740

Internet

https://elifesciences.org/articles/84740

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