Effects of multiple doses of montmorillonite, alone and in combination with activated charcoal, on the toxicokinetics of a single dose of digoxin in rats

Objective(s): A narrow margin between the therapeutic and toxic doses of digoxin can result in an increased incidence of toxicity.  Since digoxin has an enterohepatic cycle, multiple oral doses of absorbents like montmorillonite may be useful in the treatment of digoxin toxicity.Materials and Method...

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Bibliographic Details
Main Authors: Fatemeh Heydarian, Mohamad Moshiri, Ali Roohbakhsh, Maryam Akaberi, Atoosa Haghighizadeh, Ameneh Ghadiri, Negar Yeganeh Khorasani, Leila Etemad
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_22479_573816ef5ae8e6d3fac3cd04bc967705.pdf