STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions. Here the authors show STIM1 is the major isoform controlling SOCE in mouse dendritic cells and provide a mechanism for its requirement in antige...

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Bibliografski detalji
Glavni autori: Paula Nunes-Hasler, Sophia Maschalidi, Carla Lippens, Cyril Castelbou, Samuel Bouvet, Daniele Guido, Flavien Bermont, Esen Y. Bassoy, Nicolas Page, Doron Merkler, Stéphanie Hugues, Denis Martinvalet, Bénédicte Manoury, Nicolas Demaurex
Format: Članak
Jezik:English
Izdano: Nature Portfolio 2017-11-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-017-01600-6

Internet

https://doi.org/10.1038/s41467-017-01600-6

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