TLR4-mediated release of heparin-binding protein in human airways: a co-stimulatory role for IL-26

TLR4-mediated release of heparin-binding protein in human airways: a co-stimulatory role for IL-26

BackgroundBacterial infection causes accumulation of neutrophils that release antimicrobial proteins including heparin-binding protein (HBP). In human airways, this neutrophil accumulation can be re-capitulated via intrabronchial exposure to lipopolysaccharide (LPS), a Toll-like receptor 4 (TLR4) ag...

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Bibliographic Details
Main Authors: Magnus Paulsson, Eduardo I. Cardenas, Karlhans F. Che, Bettina Brundin, Margaretha Smith, Ingemar Qvarfordt, Anders Lindén
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
heparin-binding protein (HBP)
lipopolysaccharide (LPS)
toll-like receptor 4 (TLR4)
IL-26
CAP37
azurocidin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178135/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178135/full

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