Quantitative Structure – Pharmacokinetics Relationships for Plasma Protein Binding of Basic Drugs
Purpose. Binding of drugs to plasma proteins is a common physiological occurrence which may have a profound effect on both pharmacokinetics and pharmacodynamics. The early prediction of plasma protein binding (PPB) of new drug candidates is an important step in drug development process. The present...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2018-01-01
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Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/28971 |