Leech extract inhibits VEGF expression in WERI-RB-1 cells possibly via VEGF/PI3K/AKT signal pathway

Leech extract inhibits VEGF expression in WERI-RB-1 cells possibly via VEGF/PI3K/AKT signal pathway

AIM: To study the effect of leech extract on the expression of vascular endothelial growth factor(VEGF)in retinoblastoma(WERI-RB-1 cells)and the related molecular mechanism.METHODS: WERI-RB-1 cells cultured in vitro were divided into control group, 0.04U/mL leech extract group and 0.08U/mL leech ext...

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Bibliographic Details
Main Authors: Yuan-Yuan Li, Yan-Lin Zheng, Jian-Chao Li, Yan-Nian Hui, Shi-Hang Ma, Hui Huang, Fang Wang, Hong-Jie Ma
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2022-12-01
Series:Guoji Yanke Zazhi
Subjects:
leech extract
retinoblastoma
vascular endothelial growth factor(vegf)
phosphatidylinositol 3-kinase/protein kinae b(pi3k/akt)
signal pathway
Online Access:http://ies.ijo.cn/cn_publish/2022/12/202212004.pdf

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http://ies.ijo.cn/cn_publish/2022/12/202212004.pdf

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