Design, pharmacokinetic profiling, and assessment of kinetic and thermodynamic stability of novel anti-Salmonella typhi imidazole analogues
Abstract Background Typhoid fever, a disease caused by a gram negative bacterial species known as Salmonella typhi, constitutes a significant cause of morbidity and mortality, especially in developing nations of the world. Antibiotic therapy is the major treatment option currently but the rising inc...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2023-01-01
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Series: | Bulletin of the National Research Centre |
Subjects: | |
Online Access: | https://doi.org/10.1186/s42269-023-00983-5 |