An Inverse Agonist of Estrogen-Related Receptor Gamma, GSK5182, Enhances Na<sup>+</sup>/I<sup>−</sup> Symporter Function in Radioiodine-Refractory Papillary Thyroid Cancer Cells

An Inverse Agonist of Estrogen-Related Receptor Gamma, GSK5182, Enhances Na<sup>+</sup>/I<sup>−</sup> Symporter Function in Radioiodine-Refractory Papillary Thyroid Cancer Cells

Previously, we reported that an inverse agonist of estrogen-related receptor gamma (ERRγ), GSK5182, enhances sodium iodide (Na<sup>+</sup>/I<sup>−</sup>) symporter (NIS) function through mitogen-activated protein (MAP) kinase signaling in anaplastic thyroid cancer cells. This...

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Bibliographic Details
Main Authors: Thoudam Debraj Singh, Jae Eon Lee, Kwang Hee Son, Bo Ra Lee, Sang Kyoon Kim, Deepak Gulwani, Vijaya Sarangthem, Yong Hyun Jeon
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
estrogen-related receptor gamma
radioiodine-refractory papillary thyroid cancer cells
sodium iodide symporter
radioiodine uptake
radioiodine therapy
Online Access:https://www.mdpi.com/2073-4409/12/3/470

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https://www.mdpi.com/2073-4409/12/3/470

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