Fungus-Derived 3-Hydroxyterphenyllin and Candidusin A Ameliorate Palmitic Acid-Induced Human Podocyte Injury via Anti-Oxidative and Anti-Apoptotic Mechanisms

Fungus-Derived 3-Hydroxyterphenyllin and Candidusin A Ameliorate Palmitic Acid-Induced Human Podocyte Injury via Anti-Oxidative and Anti-Apoptotic Mechanisms

Diabetic nephropathy (DN) is a leading cause of end-stage renal disease. An elevated fatty acid plasma concentration leads to podocyte injury and DN progression. This study aimed to identify and characterize cellular mechanisms of natural compounds that inhibit palmitic acid (PA)–induced human podoc...

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Bibliographic Details
Main Authors: Suchada Kaewin, Karn Changsorn, Titiwat Sungkaworn, Peraya Hiranmartsuwan, Wiriya Yaosanit, Vatcharin Rukachaisirikul, Chatchai Muanprasat
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
podocytes
diabetic nephropathy
3-hydroxyterphenyllin
candidusin A
palmitic acid
Online Access:https://www.mdpi.com/1420-3049/27/7/2109

Internet

https://www.mdpi.com/1420-3049/27/7/2109

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