New synthesis of a late-stage tetracyclic key intermediate of lumateperone

New approaches have been tested for the synthesis of lumateperone intermediates. As a result of these efforts, a novel synthesis of the late-stage tetracyclic key intermediate of lumateperone starting from the commercially available quinoxaline is described. The tetracyclic skeleton was constructed...

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Bibliographic Details
Main Authors: Mátyás Milen, Bálint Nyulasi, Tamás Nagy, Gyula Simig, Balázs Volk
Format: Article
Language:English
Published: Beilstein-Institut 2022-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.18.66