Leveraging infectious disease models to interpret randomized controlled trials: Controlling enteric pathogen transmission through water, sanitation, and hygiene interventions.

Randomized controlled trials (RCTs) evaluate hypotheses in specific contexts and are often considered the gold standard of evidence for infectious disease interventions, but their results cannot immediately generalize to other contexts (e.g., different populations, interventions, or disease burdens)...

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Bibliographic Details
Main Authors: Andrew F Brouwer, Marisa C Eisenberg, Kevin M Bakker, Savannah N Boerger, Mondal H Zahid, Matthew C Freeman, Joseph N S Eisenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010748