The protective effect of gentisic acid on rheumatoid arthritis via the RAF/ERK signaling pathway

Abstract Background RAF and ERK pathways are known to be activated in human rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS), which play an important role in the pathogenesis and destruction of RA. Gentisic acid (GA) was a natural product derived from plants, which has been reported can...

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Bibliographic Details
Main Authors: Xiaojun Dong, Qi Zhang, Fujia Zeng, Mingxing Cai, Dou Ding
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-022-03006-7