Different Expression Levels of DLK2 Inhibit NOTCH Signaling and Inversely Modulate MDA-MB-231 Breast Cancer Tumor Growth In Vivo

Different Expression Levels of DLK2 Inhibit NOTCH Signaling and Inversely Modulate MDA-MB-231 Breast Cancer Tumor Growth In Vivo

NOTCH signaling is implicated in the development of breast cancer tumors. DLK2, a non-canonical inhibitor of NOTCH signaling, was previously shown to be involved in skin and breast cancer. In this work, we studied whether different levels of DLK2 expression influenced the breast cancer characteristi...

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Bibliographic Details
Main Authors: Ana-Isabel Naranjo, María-Julia González-Gómez, Victoriano Baladrón, Jorge Laborda, María-Luisa Nueda
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
DLK2
NOTCH signaling
MDA-MB-231 cells
kinase
tumor growth in vivo
Online Access:https://www.mdpi.com/1422-0067/23/3/1554

Internet

https://www.mdpi.com/1422-0067/23/3/1554

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