The role of hypoxia and radiation in developing a CTCs-like phenotype in murine osteosarcoma cells

Introduction: Cancer treatment has evolved significantly, yet concerns about tumor recurrence and metastasis persist. Within the dynamic tumor microenvironment, a subpopulation of mesenchymal tumor cells, known as Circulating Cancer Stem Cells (CCSCs), express markers like CD133, TrkB, and CD47, mak...

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Bibliographic Details
Main Authors: Martina Quartieri, Anggraeini Puspitasari, Tamara Vitacchio, Marco Durante, Walter Tinganelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1222809/full