Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State

Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State

A disintegrin and metalloproteinase 15 (ADAM15) is a member of the ADAM family of sheddases. Its genetic ablation in mice suggests that ADAM15 plays an important role in a wide variety of biological functions, including cartilage homeostasis. Nevertheless, while the substrate repertoire of other mem...

Full description

Bibliographic Details
Main Authors: Chun-Yao Yang, Simone Bonelli, Matteo Calligaris, Anna Paola Carreca, Stephan A. Müller, Stefan F. Lichtenthaler, Linda Troeberg, Simone D. Scilabra
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Membranes
Subjects:
metalloproteinases
ADAMs
ADAM15
proteomics
secretome
Online Access:https://www.mdpi.com/2077-0375/12/6/578

Internet

https://www.mdpi.com/2077-0375/12/6/578

Similar Items