Lenalidomide improves NKG2D-based CAR-T cell activity against colorectal cancer cells invitro

Introduction: Although CAR-based immunotherapy is viewed as a promising treatment for tumors, particularly hematological malignancies, solid tumors can pose challenges. It has been suggested that the immunomodulatory medication Lenalidomide (LEN) may increase the effectiveness of CAR T cells in the...

Full description

Bibliographic Details
Main Authors: Mahdi Zarei, Shahriyar Abdoli, Touraj Farazmandfar, Majid Shahbazi
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023076685