Biological characterization of a myotoxin phosphoplipase A2 homologue purified from the venom of the snake Bothrops moojeni

Biological characterization of a myotoxin phosphoplipase A2 homologue purified from the venom of the snake Bothrops moojeni

A myotoxin phospholipase A2 homologue, BmooMtx, was isolated from the venom of Bothrops moojeni by a combination of ion-exchange chromatography on DEAE-Sephacel column and gel filtration on Sephadex G-75. SDS-PAGE showed the enzyme to be a monomer with a molecular weight of 16,500. BmooMtx induced r...

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Bibliographic Details
Main Authors: MR Queiroz, CC Mamede, KC Fonseca, LCMN Canabrava, LV França, MC Silva, L Stanziola, ME Beletti, HAN Canabrava, F Oliveira
Format: Article
Language:English
Published: SciELO 2011-01-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Bothrops moojeni
hyperalgesia
myotoxin
edema
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000100007

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000100007

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