Rejuvenation of human mesenchymal stem cells using a nonintegrative and conditionally removable Sendai virus vector

Rejuvenation of human mesenchymal stem cells using a nonintegrative and conditionally removable Sendai virus vector

Abstract Human mesenchymal stem cells (hMSCs) with extended lifespan and differentiation potential that can recapitulate in vivo characteristics could significantly contribute to basic research, drug development, and cell therapy. Specifically, they could ensure a stable supply of specific cellular...

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Bibliographic Details
Main Authors: Mitsuo Oshimura, Toshiaki Tabata, Narumi Uno, Shuta Takata, Genki Hichiwa, Iori Kanazawa, Takeshi Endo, Kazuhisa Honma, Yayan Wang, Kanako Kazuki, Haochen Tu, Yuichi Iida, Satoshi Abe, Yasuhiro Kazuki
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Human mesenchymal stem cell
Sendai virus vector
Rejuvenation
Extended lifespan
Regenerative medicine
Online Access:https://doi.org/10.1038/s41598-024-74757-y

Internet

https://doi.org/10.1038/s41598-024-74757-y

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