A Plasmodium falciparum ATP-binding cassette transporter is essential for liver stage entry into schizogony

Summary: Plasmodium sporozoites invade hepatocytes and transform into liver stages within a parasitophorous vacuole (PV). The parasites then grow and replicate their genome to form exoerythrocytic merozoites that infect red blood cells. We report that the human malaria parasite Plasmodium falciparum...

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Bibliographic Details
Main Authors: Debashree Goswami, Sudhir Kumar, William Betz, Janna M. Armstrong, Meseret T. Haile, Nelly Camargo, Chaitra Parthiban, Annette M. Seilie, Sean C. Murphy, Ashley M. Vaughan, Stefan H.I. Kappe
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222004941