Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae

Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae

Anticancer agents pose a great environmental risk due to their high toxicity. The aim of the current study is to assess the toxicity of trabectedin, a cytotoxic but atypical DNA binder, to liver cell line (ZFL) and embryo-larvae of the zebrafish Danio rerio employing an innovative approach. In ZFL c...

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Bibliographic Details
Main Authors: Évila Pinheiro Damasceno, Ives Charlie-Silva, Glaucia Maria Machado-Santelli, Anali M.B. Garnique, João Agostinho Machado-Neto, Simone Aparecida Teixeira, Paula C. Jimenez, Diana Carneiro, Amadeu M.V.M. Soares, Leticia V. Costa-Lotufo, Susana Loureiro, Maria D. Pavlaki
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Environmental Advances
Subjects:
Anticancer agent
Zebrafish locomotor behavior
ZFL cells
Developmental toxicity
Cytotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666765722000436

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http://www.sciencedirect.com/science/article/pii/S2666765722000436

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