Kappa opioid receptor antagonism protects working memory performance from mild stress exposure in Rhesus macaques

Extensive preclinical and emerging clinical evidence point to an involvement of the kappa opioid receptor (KOR) in brain networks that promotes neurobehavioral stability. KOR expression in mesolimbic and mesocortical pathways has been the basis for characterizing the role of this receptor system in...

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Bibliographic Details
Main Authors: Tanya L. Wallace, William J. Martin, Amy F.T. Arnsten
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Neurobiology of Stress
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289522000686