Repeated Non-Invasive Limb Ischemic Preconditioning Confers Cardioprotection Through PKC-Ԑ/STAT3 Signaling in Diabetic Rats

Repeated Non-Invasive Limb Ischemic Preconditioning Confers Cardioprotection Through PKC-Ԑ/STAT3 Signaling in Diabetic Rats

Background/Aims: Protein kinase C(PKC)-ε activation is a mechanism of preconditioning cardioprotection but its role in repeated non-invasive limb ischemic preconditioning (rNLIP) mediated cardioprotection against myocardial ischemia/reperfusion (I/R) injury in diabetes is unknown. Methods: Eight-wee...

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Bibliographic Details
Main Authors: Chunyan Wang, Haobo Li, Sheng Wang, Xiaowen Mao, Dan Yan, Stanley S. Wong, Zhengyuan Xia, Michael G. Irwin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Repeated non-invasive limb ischemic preconditioning
Myocardial ischemia injury
PKC-ε
STAT3
Diabetes
Online Access:https://www.karger.com/Article/FullText/488047

Internet

https://www.karger.com/Article/FullText/488047

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