The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin
Somatostatin is a peptide hormone that exerts antisecretory and antiproliferative activities on some human tumors. The Ku70/86 heterodimer acts as regulatory subunit of the DNA dependent protein kinase and its DNA binding activity mediates DNA double strands breaks repair that is crucial to maintain...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2009-06-01
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Series: | European Journal of Histochemistry |
Online Access: | https://www.ejh.it/index.php/ejh/article/view/873 |