Expanding Mouse-Adapted Yamagata-like Influenza B Viruses in Eggs Enhances In Vivo Lethality in BALB/c Mice

Despite the yearly global impact of influenza B viruses (IBVs), limited host range has been a hurdle to developing a readily accessible small animal disease model for vaccine studies. Mouse-adapting IBV can produce highly pathogenic viruses through serial lung passaging in mice. Previous studies hav...

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Bibliographic Details
Main Authors: Matthew J. Pekarek, Erika M. Petro-Turnquist, Adam Rubrum, Richard J. Webby, Eric A. Weaver
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/6/1299