Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism

Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism

Introduction. Isoproterenol treatment of Brown Norway and Lewis rats (high and low plasma angiotensin-I-converting enzyme activity, respectively) results in similar cardiac hypertrophy but higher cardiac fibrosis in Brown Norway rats. Materials and methods. Rats were infused in vivo with isoproteren...

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Bibliographic Details
Main Authors: Miguel Copaja Soto, Rodrigo Valenzuela, Adiela Saldaña, María Paz Ocaranza, Jorge E. Jalil, Carlos Vio, Paul Lijnen, Gamaliel E. Ordenes, Raul Vivar Sanchez, Sergio Lavandero, Guillermo Díaz-Araya
Format: Article
Language:English
Published: SAGE Publications 2008-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320308096408

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https://doi.org/10.1177/1470320308096408

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