Effect of Carrier Lipophilicity and Preparation Method on the Properties of Andrographolide–Solid Dispersion

Effect of Carrier Lipophilicity and Preparation Method on the Properties of Andrographolide–Solid Dispersion

Solid dispersion (SD) is a useful approach to improve the dissolution rate and bioavailability of poorly water-soluble drugs. This work investigated the effects of carrier material lipophilicity and preparation method on the properties of andrographolide (AG)⁻SD. The SDs of AG and the carr...

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Bibliographic Details
Main Authors: Guowei Zhao, Qingyun Zeng, Shoude Zhang, Youquan Zhong, Changhao Wang, Yashao Chen, Liquan Ou, Zhenggen Liao
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Pharmaceutics
Subjects:
andrographolide
solid dispersion
carrier lipophilicity
preparation method
Online Access:https://www.mdpi.com/1999-4923/11/2/74

Internet

https://www.mdpi.com/1999-4923/11/2/74

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