Differential Gene Expression Signatures and Cellular Signaling Pathways induced by Lamin A/C Transcript Variants in MCF7 Cell Line

Differential Gene Expression Signatures and Cellular Signaling Pathways induced by Lamin A/C Transcript Variants in MCF7 Cell Line

Background: Lamins are the major component of nuclear lamina. Alternative splicing of the 12 exons comprising lamin A/C gene creates five known transcript variants, lamin A, lamin C, lamin AΔ10, lamin AΔ50, and lamin C2. The main objective for this study was to examine the association of critical pa...

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Bibliographic Details
Main Authors: Lin Batha, Mohammad Azhar Aziz, Mahmoud Zhra, Jasmine Holail, Wedad S. Al-Qahtani, Rajaa Fakhoury, Ahmad Aljada
Format: Article
Language:English
Published: IMR Press 2023-06-01
Series:Frontiers in Bioscience-Landmark
Subjects:
lamin a/c transcript variants
senescence
laminopathies
nuclear lamins
ion torrent
Online Access:https://www.imrpress.com/journal/FBL/28/6/10.31083/j.fbl2806113

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https://www.imrpress.com/journal/FBL/28/6/10.31083/j.fbl2806113

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