Successful Clearance of 300 Day SARS-CoV-2 Infection in a Subject with B-Cell Depletion Associated Prolonged (B-DEAP) COVID by REGEN-COV Anti-Spike Monoclonal Antibody Cocktail

Successful Clearance of 300 Day SARS-CoV-2 Infection in a Subject with B-Cell Depletion Associated Prolonged (B-DEAP) COVID by REGEN-COV Anti-Spike Monoclonal Antibody Cocktail

A 59-year-old male with follicular lymphoma treated by anti-CD20-mediated B-cell depletion and ablative chemotherapy was hospitalized with a COVID-19 infection. Although the patient did not develop specific humoral immunity, he had a mild clinical course overall. The failure of all therapeutic optio...

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Bibliographic Details
Main Authors: Arnaud C. Drouin, Marc W. Theberge, Sharon Y. Liu, Allison R. Smither, Shelby M. Flaherty, Mark Zeller, Gregory P. Geba, Peter Reynaud, W. Benjamin Rothwell, Alfred P. Luk, Di Tian, Matthew L. Boisen, Luis M. Branco, Kristian G. Andersen, James E. Robinson, Robert F. Garry, Dahlene N. Fusco
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
B-DEAP COVID-19
B-cell depletion associated prolonged COVID-19
COVID-19
SARS-CoV-2 persistence
virus mutations
anti-CD20-mediated B-cell depletion
Online Access:https://www.mdpi.com/1999-4915/13/7/1202

Internet

https://www.mdpi.com/1999-4915/13/7/1202

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